All aminoglycosides have the potential to produce

Periods of time to large wounds, burns, or any denuded skin, particularly if Intoxication may occur when aminoglycosides are applied topically for prolonged Gentamicin: While aminoglycosides are absorbed poorly from skin, Vestibular dysfunction is noted during the course of treatment, discontinue use

The cochlea or vestibular apparatus from prolonged contact. The possibility of transmitting infection to the middle ear as well as damaging Thoroughly to be certain the tympanic membrane is not ruptured in order to avoid Treatments, therapy with a rapidly acting corticosteroid should be considered inД«efore instilling any medication into the ear, examine the external ear canal Patients presently receiving or recently withdrawn from corticosteroid Result in endogenous steroid production inhibition following drug withdrawal. Use of corticosteroids, depending on dose, duration, and specific steroid, may Prolonged use or overdosage may produce adverse Sodium retention, potassium loss, fluid retention, weight gain, polydipsia,ДЄnd/or polyuria. Patients should beД¬losely observed for the usual signs of adrenocorticoid overdosage which include Oral ingestion of some topical corticosteroid preparations. Adverse systemic reactions have been observed following the Treatment, discontinue use of OTOMAX immediately and flush the ear canalДЄdministration of recommended doses of OTOMAX beyond 7 days may result inДЄvoid ingestion. If hearing or vestibular dysfunction is noted during the course of Warnings: The use of OTOMAX has been associated with deafness or partial hearing loss inДЄ small number of sensitive dogs (eg, geriatric). Shake well before use when using the 215 gram bottle.ДЇederal law restricts this drug to use by or on the order of Oil-based system containing a plasticized hydrocarbon gel. Veterinary equivalent to 3 mg gentamicin base betamethasone valerate, USPД®quivalent to 1 mg betamethasone and 10 mg clotrimazole, USP in a mineral Do not use in dogsДЄctive Ingredients: Each gram of OTOMAX contains gentamicin sulfate Use of drugs known to induce ototoxicity should be avoided. Treatment should be discontinued and appropriate therapy instituted. TherapyД¬ontraindications: If hypersensitivity to any of the components occurs, Instill 8 drops (4 drops from the 215 gД«ottle) twice daily into the ear canal of dogs weighing 30 lbs. After verifying that the eardrum is intact, instill 4Дrops (2 drops from the 215 g bottle) of OTOMAX twice daily into the ear canal Excessive hair should be clippedДЇrom the treatment area. Remove foreign material, debris, crusted exudates,Д®tc., with suitable non-irritating solutions. Resistance to clotrimazole is very rareДЄmong the fungi that cause superficial mycoses.Дosage and Administration: The external ear should be thoroughly cleanedДЄnd dried before treatment. The primary action of clotrimazole is against dividingД¬lotrimazole exhibits fungistatic and fungicidal activityДЄgainst isolates of Trichophyton rubrum, Trichophyton mentagrophytes,Д®pidermophyton floccosum, Microsporum canis, Candida spp., and Malassezia The treatment of dermal infections caused by various species of pathogenicДermatophytes and yeasts.

Clotrimazole: Clotrimazole is a broad-spectrum antifungal agent that is used for.

Systemically administered corticosteroids.

Once absorbed through the skin, topicalД¬orticosteroids are handled through pharmacokinetic pathways similar to InflammationД¬an increase percutaneous absorption. Topical corticosteroids can be absorbed from normal, intact skin. Management of corticosteroid-responsive otitis externa. To provide anti-inflammatory and anti-pruritic activity in the topical Betamethasone, an analog of prednisolone, has a high degree ofД¬orticosteroid activity and a slight degree of mineralocorticosteroid activity.Д«etamethasone valerate, the 17-valerate ester of betamethasone, has been shown Betamethasone: Betamethasone valerate is a synthetic adrenocorticoid forДermatologic use.Gentamicin is active against the following organisms commonly isolated fromД¬anine ears: Staphylococcus aureus, other Staphylococcus spp., PseudomonasДЄeruginosa, Proteus spp., and Escherichia coli. Inhibiting normal protein synthesis in susceptible microorganisms. Gentamicin: Gentamicin sulfate is an aminoglycoside antibiotic activeДЄgainst a wide variety of pathogenic gram-negative and gram-positive bacteria.Otomax reduces discomfort, redness, swelling, exudate, and odor, and exerts a strong By virtue of it's three components - Gentamicin-Betamethasone-Clotrimazole - Otomox has antibacterial, anti-inflammatory, and antifungalДЄctivity.

Otomax Ointment Antimicrobial - Anti-Inflammatory Otomax Ointment For Dogs is indicated for the treatment of canine acute andД¬hronic otitis externa associated with yeast (Malassezia pachydermatis) and/or bacteria susceptible to gentamicin.

Otomax ointment dogs and cats